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The 1995 Tokyo Subway Attack
Members of the Aum Shinrikyo cult first used the chemical nerve agent sarin (GB) in June 1994 during an attempt to assassinate members of a 3-judge panel hearing a case against the sect in Matsumoto, Japan. This incident left 7 people dead and prompted several hundred people to seek medical attention, despite the fact that there had only been 3 intended targets. [3]

Less than a year later, on March 20, 1995, Aum Shinrikyo carried out a terrorist attack intended to inflict casualties on a much larger scale, releasing sarin in 5 separate cars on 3 different Tokyo subway lines during the height of the morning rush hour. Cult members concealed the liquid sarin in lunch boxes and soft drink containers, then punctured these containers with the sharpened tips of their umbrellas as they exited the cars, quickly releasing sarin vapor into the air. [9] The sarin used by Aum Shinrikyo in the subway attacks was diluted, and although 12 people were killed, the death toll would have been considerably higher if pure sarin had been released in the same manner. Even so, more than 1,000 civilians sustained serious injury and approximately 5,500 people sought medical attention following the attacks. [3]

The emergency response to the Tokyo subway attacks exposed a number of vulnerabilities and lack of preparedness on the part of first responders, HAZMAT units, and hospitals. One of the train lines continued to run for nearly 90 minutes after the initial attack, contaminating each station it passed through. And it took almost 3 hours after the attack for the military to accurately assess the use of sarin and notify emergency response officials. Approximately 10% of the 1,300 fire department responders became victims themselves and needed treatment due to failure to take protective measures. [13]


Stockpiles, Treaties, and Violations | The 1995 Tokyo Subway Attack | An Ongoing Risk

The DuoDote™ Auto-Injector (atropine 2.1 mg/0.7 mL and pralidoxime chloride 600 mg/2 mL) is indicated for the treatment of poisoning by organophosphorus nerve agents as well as organophosphorus insecticides.

IMPORTANT SAFETY INFORMATION

The DuoDote Auto-Injector is intended as an initial treatment of the symptoms of organophosphorus insecticide or nerve agent poisonings; definitive medical care should be sought immediately. The DuoDote Auto-Injector should be administered by Emergency Medical Services personnel who have had adequate training in the recognition and treatment of nerve agent or insecticide intoxication.

Individuals should not rely solely upon agents such as atropine and pralidoxime to provide complete protection from chemical nerve agents and insecticide poisoning. Primary protection against exposure to chemical nerve agents and insecticide poisoning is the wearing of protective garments including masks designed specifically for this use. Evacuation and decontamination procedures should be undertaken as soon as possible. Medical Personnel assisting evacuated victims of nerve agent poisoning should avoid contaminating themselves by exposure to the victim's clothing.

In the presence of life-threatening poisoning by organophosphorus nerve agents or insecticides, there are no absolute contraindications to the use of the DuoDote Auto-Injector. When symptoms of poisoning are not severe, DuoDote Auto-Injector should be used with extreme caution in people with heart disease, arrhythmias, recent myocardial infarction, severe narrow angle glaucoma, pyloric stenosis, prostatic hypertrophy, significant renal insufficiency, chronic pulmonary disease, or hypersensitivity to any component of the product.

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DuoDote Auto-Injector, the DuoDote Logo, Mark I Kit, and BinaJect are trademarks of Meridian Medical Technologies™, Inc., a wholly owned subsidiary of King Pharmaceuticals®, Inc. Copyright ® 2010 Meridian Medical Technologies™, Inc., a wholly owned subsidiary of King Pharmaceuticals®, Inc. All rights reserved. MMT6193 06/2009