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With its 2-in-1 auto-injector technology, DuoDote™ Auto-Injector is even easier to use than its predecessor, the Mark I™ Kit. An important part of being prepared for the unexpected is familiarity with administration techniques and dosing parameters.

How to Inject DuoDote
DuoDote provides a rapid, user-friendly readiness solution for first responders who are faced with chemical nerve agent or organophosphorus insecticide poisoning. Please click here to learn the simple steps for quick and accurate use of the DuoDote Auto-Injector.

Dosing Parameters
Each DuoDote Auto-Injector contains fixed-ratio doses of atropine and pralidoxime chloride. Multiple doses of both antidotes are often required, based upon the severity of symptoms.* Please click here to learn about dosing parameters for the DuoDote Auto-Injector.

Download Training Resources
First responders, training specialists, and managers can all benefit from clear, concise instructions. Click here to learn more about DuoDote training resources from Meridian Medical Technologies, including a downloadable multimedia presentation.

Who Can Order DuoDote?
If you are already a customer of Meridian Medical Technologies, your designated account representative can process your DuoDote order immediately. New customers can set up an account quickly by telephone or E-mail. Please click here for more information.

*No more than 3 doses of DuoDote should be administered unless definitive medical care (ie, hospitalization, respiratory support) is available. [1]

The DuoDote™ Auto-Injector (atropine 2.1 mg/0.7 mL and pralidoxime chloride 600 mg/2 mL) is indicated for the treatment of poisoning by organophosphorus nerve agents as well as organophosphorus insecticides.

IMPORTANT SAFETY INFORMATION

The DuoDote Auto-Injector is intended as an initial treatment of the symptoms of organophosphorus insecticide or nerve agent poisonings; definitive medical care should be sought immediately. The DuoDote Auto-Injector should be administered by Emergency Medical Services personnel who have had adequate training in the recognition and treatment of nerve agent or insecticide intoxication.

Individuals should not rely solely upon agents such as atropine and pralidoxime to provide complete protection from chemical nerve agents and insecticide poisoning. Primary protection against exposure to chemical nerve agents and insecticide poisoning is the wearing of protective garments including masks designed specifically for this use. Evacuation and decontamination procedures should be undertaken as soon as possible. Medical Personnel assisting evacuated victims of nerve agent poisoning should avoid contaminating themselves by exposure to the victim's clothing.

In the presence of life-threatening poisoning by organophosphorus nerve agents or insecticides, there are no absolute contraindications to the use of the DuoDote Auto-Injector. When symptoms of poisoning are not severe, DuoDote Auto-Injector should be used with extreme caution in people with heart disease, arrhythmias, recent myocardial infarction, severe narrow angle glaucoma, pyloric stenosis, prostatic hypertrophy, significant renal insufficiency, chronic pulmonary disease, or hypersensitivity to any component of the product.

Please click here to view full prescribing information for DuoDote.

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© 2007 Meridian Medical Technologies™ Inc., a subsidiary of King Pharmaceuticals®, Inc. DuoDote™ Auto-Injector, the DuoDote logo, BinaJect™, and Mark I™ Kit are trademarks of Meridian Medical Technologies™, Inc. AtroPen® is a registered trademark of Meridian Medical Technologies™, Inc. MMT 4908 10/07®