FAQs | How to Order | Contact Us | Prescribing Information | Important Safety Information
 Register  |  Login

In most emergency situations, there is no time to consult reference books, only time to react. Therefore, it's important to be prepared for anything and be knowledgeable about all poisoning risks. Few emergency responders have adequate information about chemical nerve agents (CNAs) and organophosphorus insecticides (OPIs).

Having DuoDote™ Auto-Injectors on hand can prove to be life-saving for both responders and patients. But first, it's important to be aware of the types of CNAs and OPIs that can cause harm and be able to identify the associated signs and symptoms of poisoning. This section will provide you with useful background information on CNAs and OPIs.

Four Key Chemical Nerve Agents
Chemical nerve agents are some of the most toxic chemical agents known. Although several different types may exist, 4 are typically regarded as the most deadly. Please click here to learn more about tabun (GA), sarin (GB), soman (GD), and VX (which has no common name).

Key Insecticide Categories
In rare but severe situations, commonly used insecticides can cause serious harm to humans. Please click here to learn about different insecticide categories, and specifically about those most often implicated in poisonings, injuries, and illnesses—organophosphorus insecticides.

Physiologic Effects of CNA and OPI Poisoning
The effects of CNAs and OPIs can appear within seconds and, in severe cases, death can result within a few minutes. [20] Please click here to learn about the signs and symptoms associated with CNA and OPI poisoning and to read a clinical explanation about the physiologic effects of these compounds.

The DuoDote™ Auto-Injector (atropine 2.1 mg/0.7 mL and pralidoxime chloride 600 mg/2 mL) is indicated for the treatment of poisoning by organophosphorus nerve agents as well as organophosphorus insecticides.

IMPORTANT SAFETY INFORMATION

The DuoDote Auto-Injector is intended as an initial treatment of the symptoms of organophosphorus insecticide or nerve agent poisonings; definitive medical care should be sought immediately. The DuoDote Auto-Injector should be administered by Emergency Medical Services personnel who have had adequate training in the recognition and treatment of nerve agent or insecticide intoxication.

Individuals should not rely solely upon agents such as atropine and pralidoxime to provide complete protection from chemical nerve agents and insecticide poisoning. Primary protection against exposure to chemical nerve agents and insecticide poisoning is the wearing of protective garments including masks designed specifically for this use. Evacuation and decontamination procedures should be undertaken as soon as possible. Medical Personnel assisting evacuated victims of nerve agent poisoning should avoid contaminating themselves by exposure to the victim's clothing.

In the presence of life-threatening poisoning by organophosphorus nerve agents or insecticides, there are no absolute contraindications to the use of the DuoDote Auto-Injector. When symptoms of poisoning are not severe, DuoDote Auto-Injector should be used with extreme caution in people with heart disease, arrhythmias, recent myocardial infarction, severe narrow angle glaucoma, pyloric stenosis, prostatic hypertrophy, significant renal insufficiency, chronic pulmonary disease, or hypersensitivity to any component of the product.

Please click here to view full prescribing information for DuoDote.

Site Map | References | Copyright | Privacy Policy | Terms of Use | About Meridian


© 2007 Meridian Medical Technologies™ Inc., a subsidiary of King Pharmaceuticals®, Inc. DuoDote™ Auto-Injector, the DuoDote logo, BinaJect™, and Mark I™ Kit are trademarks of Meridian Medical Technologies™, Inc. AtroPen® is a registered trademark of Meridian Medical Technologies™, Inc. MMT 4908 10/07®